Piroctone Olamine High-efficiency Mild Anti-dandruff Scalp Care Raw Material
Product Name: Piroctone Olamine (OCT)
Chemical Name: 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone 2-aminoethanol salt
INCI Name: Piroctone Olamine
CAS Number: 68890-66-4
EINECS Number: 272-574-2
Molecular Formula: C16H29N3O3
Molecular Weight: 311.42
Purity: ≥99.0% (HPLC)
Appearance: White to Light Yellow Crystalline Powder, Slight Characteristic Odor
Solubility: Soluble in ethanol, propylene glycol and surfactant systems, slightly soluble in water
Effective pH Range: 4.0-9.0, excellent thermal and pH stability
Grade: Cosmetic Grade, High-efficiency Anti-dandruff Grade, Global Regulatory Compliant
MOQ: 100g / 1KG
Shelf Life: 24 months (sealed, light-proof, cool and dry storage below 25℃)
Product Features: Mild and low irritation, root cause anti-dandruff, available for both rinse-off and leave-on products, no scalp dryness, assist in hair care
Piroctone Olamine, OCT Anti-dandruff Agent, Mild Scalp Care Ingredient, Anti-malarassez Functional Raw Material, Leave-on Hair Care Additive, Broad-spectrum Antifungal, Scalp Itching Relief, Global Compliant Cosmetic Raw Material
Piroctone Olamine-CAS 68890-66-4
Piroctone Olamine (OCT) is a high-efficiency and mild new-generation anti-dandruff scalp care cosmetic raw material.
Different from traditional zinc pyrithione (ZPT) anti-dandruff ingredients with strong irritation and dryness, it inhibits the growth of Malassezia, the core cause of dandruff, through metal ion chelation mechanism, fundamentally solving scalp itching, flaking and oily dandruff problems.
With ultra-mild properties, it does not damage scalp barrier or cause dry and frizzy hair after use.
It is the only globally approved anti-dandruff active ingredient applicable to both rinse-off and leave-on hair care products.
It features wide pH adaptability, high-temperature processing stability and excellent formula compatibility, and also has mild broad-spectrum antibacterial and preservative auxiliary effects.
It is a mainstream safe and efficient functional raw material for high-end mild anti-dandruff and healthy scalp care formulas.



Key Benefits
• Root Cause Anti-dandruff & Anti-itching: Targetedly inhibits Malassezia reproduction, eliminates dandruff from the source, relieves persistent scalp itching, and improves oily scalp flaking.
• Ultra-mild & Barrier-friendly: Far lower irritation than traditional anti-dandruff agents, no scalp stinging or hair dryness, friendly to sensitive scalp.
• Dual Application for Rinse-off & Leave-on: Globally approved for both washed hair care and leave-on scalp care products, wide application scenarios and strong practicability.
• Excellent Formula Stability: Stable activity in pH 4.0-9.0 and conventional high-temperature production processes, no failure or precipitation.
• Broad-spectrum Bacteriostatic & Auxiliary Preservative: Inhibits various fungi and bacteria, assists in stabilizing formula system and extending product shelf life.
• Optimize Scalp Environment: Regulates scalp oil balance, improves scalp redness and discomfort, creates clean and healthy scalp microenvironment.
Applications
• Anti-dandruff Shampoo Series: Mild anti-dandruff shampoo, oil-control fluffy shampoo, sensitive scalp dedicated hair cleansing products.
• Leave-on Scalp Care Series: Scalp soothing essence, anti-itching scalp lotion, oil-balancing scalp care spray.
• Functional Hair Care Series: Nourishing hair conditioner, scalp repair cream, anti-inflammatory and soothing hair care products.
• Mild Cleaning Series: Gentle body wash, antibacterial cleansing products, daily mild bacteriostatic skin care formulas.
• Problem Scalp Management: Seborrheic scalp maintenance, oily itchy scalp conditioning, repeated dandruff repair products.
• High-end Clean Hair Care: Zero irritation clean hair care formulas, natural mild functional hair care products.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Piroctone Olamine | Compliant |
Appearance (25℃) | White to Light Yellow Crystalline Powder | White Uniform Crystalline Powder |
Purity (HPLC) | ≥99.0% | 99.5% |
Melting Point | 130℃ - 135℃ | 131.6℃ - 133.2℃ |
Loss on Drying | ≤0.5% | 0.20% |
Ash Content | ≤0.1% | 0.06% |
pH Value (1% Alcohol Solution) | 6.0-8.0 | 7.1 |
Heavy Metal (Pb) | ≤1ppm | <0.5ppm |
Arsenic (As) | ≤0.2ppm | Qualified |
Microorganism | Total Plate Count ≤100CFU/g | Qualified |
Conclusion | Meets global cosmetic grade raw material standards | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the core advantage of OCT compared with traditional ZPT? A1: Lower irritation, no dry hair after use, supports leave-on products, more stable formula, no precipitation, safer for sensitive scalp.
• Q2: What is the legal and recommended addition dosage? A2: Global legal limit 1.0%; conventional shampoo 0.2%-0.5%, leave-on scalp care 0.1%-0.3%, functional cleansing 0.05%-0.2%.
• Q3: What is the correct feeding and dissolving method? A3: Pre-dissolve with ethanol or propylene glycol at normal temperature first, then add into surfactant system for uniform dispersion.
• Q4: What ingredients are suitable for compounding? A4: Compatible with most surfactants, can be compounded with panthenol and plant soothing ingredients to enhance scalp repair effect.
• Q5: Does high-temperature production affect its efficacy? A5: Stable heat resistance, no activity loss in conventional cosmetic high-temperature processing, suitable for mass production.
• Q6: Do you support sample testing and bulk supply? A6: Support small batch trial samples and bulk stable supply, provide complete qualification reports and technical guidance.
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